My mother had valve replacement surgery about 8 yrs ago. No pacemaker but I was wondering if it would effect her biofeedback scan? And, my sister in-law is having some issues with her liver numbers and going to see a specialist. Any suggestions?

First step for everybody is to run Terrain protocol. You can run that on Spooky Remote and takes 11 days non stop to complete.
If person has amalgam fillings omit mercury detox and use activated charcoal instead.

Re Mother with valve surgery, IMO rifing using contact and Spooky Pulse biofeedback (BFB) won't be an issue. 
Consider the following Programs in a healing Shell Preset:
Heart Valve Diseases ETDF 
Heart General
Heart Function Normalize
Heart Function Balance programs 

Re sister in-law liver issue. You will need doctor's report for more guidance.
Consider the following programs:
Detox 3 Toxins in the Kidneys and Liver
Inflammation General
Liver Support

For every body I recommend to run cold wrist laser using Blood Cleanser cancer XTRA program. Load this program into Presets->Home button->Shell (Empty) Presets->Spooky Cold Laser - JW How often to run this program? That’s something you need to experiment with. My daughter for example when she feels fatigued will run this program and says she gets energy boost and feels better.

You will find each person needs at least two Generators (XM or GX (GenX).

For more details, please check the link:
https://www.spooky2.com/forums/viewtopic.php?f=18&t=9880