It's in Notes made by the creator, so I suggest that you run these two presets first.
No, you just run the first two presets once (or twice) first, before anything else, and not always. Then you can run any other DH presets, however the author recommends to run the six first presets in order. When you are done with them you can choose any other of the rest, and you do not have to run the Spiritual Wellness and Chakra presets anymore.
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