A person had stroke for years. Right side of body was immobile. Left leg is very weak possibly due to infection, nutritional issues. The biofeedback pad is supposed to be used one on the right hand and the other on the left ankle. Would it still work?

Yes this should still work, since the body will still conduct current from one side to the other and feedback is based on the heart's response.

If you rather use the left wrist, right ankle you can do so. The entire purpose of one side to the other is to incorporate as much of the body into the current flow as possible.

For more details, please check the link:
http://www.spooky2.com/forums/viewtopic.php?f=5&t=6273

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